Author's Note: Yes, we know that makes no sense to 95% of the reading audience. Screw you, it amused us. The point is that Aya from Weiss Kreuz, the character
in the first box, is voiced by Koyasu Takehito, the ultimate bishounen seiyuu. He does, however, tend to play the same character all the time, with the result that Aya's line
could be said by:
Hotohori from Fushigi Yuugi (that's Nuriko from FY speaking)
Zechs Merquise from Gundam Wing (Treize speaking)
Kira Sakuya from Angel Sanctuary (Setsuna speaking)
Arimasa from Kashou no Tsuki (Kagetsu speaking)
Each of the speaking characters is a semi-sortof-fangirl love interest for the Koyasu character, hence their reaction to the line.

Damn, that explanation took longer than the strip did...